The precise and fair implementation of laws in the judicial policy of legal systems is inevitable.In two-value or Aristotelian logic, the foundations and principles of science are subject to a fixed rule that thing is either right or wrong.Fuzzy thinking in the interpretation and explanation of laws, both quantitatively and qualitatively, Round Tab
Xiaoning Lin,1,* Rong Huang,2,* Yanlin Huang,1,* Kai Wang,3 Heng Li,1 Yiheng Bao,1 Chaohui Wu,4 Yi Zhang,5 Xinhua Tian,1 Xiaomin Wang6 1Department of Neurosurgery, Zhongshan Hospital Xiamen University, Xiamen, 361004, People’s Republic of China; 2Department of Child Health, Women and Children’s Hospital, Xiamen University, Xiamen, 36100
Abstract Background Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches.The small-molecule MDM2 antagonist Nutlin-3a activates the p53 pathway and efficiently induces apoptosis in tumours with amplified MDM2 gene and overexpression Whiteline of MDM2 protein.However, the majority of human sarcomas